We have some exciting news to share! The Motley Fool UK has now become The Twelfth Magpie -- an independent, UK-owned company, led by our long-serving UK management team — Mark Rogers, Chris Nials and Heather Adlington. In practical terms, it’s the same team you know, now fully focused on serving our UK readers and members.

Just as importantly, our approach remains unchanged: long-term, jargon-free, and on your side. This site is our new home, and there will be extra tweaks made across the coming few days as we settle in. So if anything looks a little off, please bear with us!

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

How AstraZeneca plc Could Struggle To Repeat A 5-Year Gain of 78%

AstraZeneca plc (LON:AZN) could loose a third of its value in the next five years.

| More on:

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

The shares of AstraZeneca (LSE: AZN) (NYSE: AZN.US), currently trading at around £46, have soared 78% over the last five years, outperforming the FTSE 100, which has gained 53%.

A good chunk of the gain has come on the back of the recent takeover offer from US giant Pfizer. Before rumours of the offer emerged, AstraZeneca’s shares were trading below £38.

XXX

While investors buying into the UK firm today at £46 could potentially see a relatively quick gain of 20% if Pfizer sweetened its £50 bid to £55 — and was successful, of course — they could equally see a sharp 20% reversal back to below £38 if the deal failed to go ahead.

Furthermore, I think the shares have the potential to be 33% lower than today’s price in five years’ time.

Here’s how

AZN

As most readers will know by now, AstraZeneca’s revenue and earnings have been falling over the last couple of years, due to expiring patent protection on some of its blockbuster drugs. Furthermore, City analysts don’t expect the declines to bottom out until 2017, when earnings per share (EPS) is expected to floor at around 234p.

With last year’s EPS at 306p, and EPS for the year ending December 2018 forecast to be 253p, we’re looking at a compound annual growth rate of minus 3.7%.

If we were generous, and rated AstraZeneca’s 2018 EPS of 253p at the FTSE 100’s long-term average historic P/E of 16, we’d see the share price at around £40.50 — 12% lower than today.

Gloomy scenario

But, if takeover talk was off the agenda, and the gloomy earnings scenario played out according to analysts’ forecasts, it wouldn’t be too hard to imagine AstraZeneca rated on the P/E it was at before Pfizer’s recent interest; namely 12.3. If that were to be the case, the shares would be trading at not much more than £31 five years from now — 33% lower than today.

The negative return would be mitigated by dividends, although the most bearish analysts are forecasting a cut within the next couple of years. Still, taking the consensus, we’d see 844p paid out over the period. Put another way, a £1,000 investment in AstraZeneca today would deliver £184 in dividends. Pretty decent income, but little compensation for a potential capital fall of 33%.

Long-term shareholders who’ve cashed-in for a good return on the back of Pfizer’s offer will be delighted, but anyone buying into AstraZeneca at the current price faces the risk of a short, sharp shock and a very long-haul recovery if the takeover goes pear-shaped.

G A Chester does not own any shares mentioned in this article.

More on Investing Articles

Friends and sisters exploring the outdoors together in Cornwall. They are standing with their arms around each other at the coast.
Investing Articles

£503 buys 14 shares in this FTSE 250 stock that returned 23.9% annually for the last 15 years

This FTSE 250 stock has averaged a huge return for 15 years. At today's price, £503 buys 14 shares. But…

Read more »

Black woman using loudspeaker to be heard
Investing Articles

£1,000 buys 25 shares in this FTSE 100 stock that’s returned 29.2% annually for the last 10 years

This FTSE 100 mining stock has returned close to 30% a year for a decade. At 3,995p, £1,000 buys 25…

Read more »

Female student sitting at the steps and using laptop
Investing Articles

Down 47%, is this growth stock finally worth buying in May?

With a £288m order book and a hidden pipeline of defence and nuclear contracts, is this growth stock now too…

Read more »

House models and one with REIT - standing for real estate investment trust - written on it.
Investing Articles

2 REITs yielding 7%+ to consider for passive income in 2026

A REIT backed by the NHS and another backed by Tesco and Sainsbury's with both yielding 7%+. Here's why I'm…

Read more »

Woman riding her old fashioned bicycle along the Beach Esplanade at Aberdeen, Scotland.
Investing Articles

Just 97 shares of this UK dividend stock generate £238 in passive income

A 5.7% yield, £238 in passive income from just 97 shares, and one of the most divisive dividend stocks on…

Read more »

ISA coins
Investing Articles

£10,000 in an ISA generates a second income of…

The London Stock Exchange is home to some of the world's most generous dividends. But how big a second income…

Read more »

Shot of a senior man drinking coffee and looking thoughtfully out of a window
Investing Articles

Expert recommendations: 2 top income stocks yielding 7%+!

With yields of 7.2% and 7.8% respectively, these two income stocks are catching the eyes of institutional analysts. Should investors…

Read more »

Illustration of flames over a black background
Investing Articles

3 top income-focused stocks to buy in May 2026, according to experts

Looking for a stock to buy for income in May 2026? Experts have flagged these three UK dividend shares as…

Read more »