We have some exciting news to share! The Motley Fool UK has now become The Twelfth Magpie -- an independent, UK-owned company, led by our long-serving UK management team — Mark Rogers, Chris Nials and Heather Adlington. In practical terms, it’s the same team you know, now fully focused on serving our UK readers and members.

Just as importantly, our approach remains unchanged: long-term, jargon-free, and on your side. This site is our new home, and there will be extra tweaks made across the coming few days as we settle in. So if anything looks a little off, please bear with us!

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

GlaxoSmithKline plc vs Shire PLC: Which Wins On Income And Growth?

GlaxoSmithKline plc (LON: GSK) and Shire PLC (LON: SHP) are two great companies, but which should you pick?

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

GlaxoSmithKline (LSE: GSK) (NYSE: GSK.US) and Shire (LSE: SHP) (NASDAQ: SHPG.US) are similar companies but with very different outlooks.

On one hand, Glaxo is struggling to grow but is returning huge amounts of cash to investors.

XXX

On the other hand, Shire is growing rapidly, although the company’s minuscule dividend payout leaves a lot to be desired.

So, which company should you choose for income and growth?

Bigger is not better
GlaxoSmithKline

Shire has become the shining star of the UK’s biotechnology sector during the past five years. Indeed, since 2008 Shire’s earnings per share have nearly doubled and are expected to grow a further 26% this year.

The company has been able to achieve this growth by focusing on specialist treatments, such as VYVANSE, a treatment for the maintenance of ADHD in adults. This narrowed focus has ensured that Shire has continued to prosper, while the majority of the company’s larger peers report falling sales and profits, as they lose exclusive manufacturing rights for a number of key ‘blockbuster’ treatments. 

What’s more, Shire is currently investing for future growth through targeted acquisitions. The company recently acquired Lumena Pharmaceuticals, a biopharmaceutical company with late-stage compounds for rare gastrointestinal and hepatic conditions, once again reinforcing Shire’s dominance within the niche pharmaceutical sector. 

But while Shire has been growing rapidly during the past five years, Glaxo has struggled. Indeed, despite being one of the largest pharmaceutical companies in the world, Glaxo’s earnings per share have actually fallen 7% since 2009, as patent expirations have taken their toll on sales.

That being said, Glaxo has a healthy pipeline of new treatments under development and the company’s R&D boffins have brought 15 new treatments to market during the past year or so.

However, Glaxo’s sales are not expected to return to growth until 2015.

Still, Glaxo’s management remains proactive and recently signed a deal with Swiss pharmaceutical giant Novartis, which will see the consumer divisions of the two biotechnology giants merge, creating a ‘world-leading’ consumer healthcare business with £6.5bn in revenue in 2013.

Additionally, Novartis is acquiring Glaxo’s oncology portfolio for $14.5bn and Glaxo is using $5.25bn of this cash to acquire Novartis’ vaccines business.

Valuation and income

Shire’s growth during the past few years has been impressive and investors have been willing to pay a premium for this growth. In particular, Shire currently trades at a historic P/E of 22, compared to Glaxo’s ratio of 15, making Shire look expensive. 

Nevertheless, with Shire’s earnings expected to jump 26% this year, the company trades at a forward P/E of 17.3 and a PEG ratio of 0.7, indicating that the company’s shares offer growth at a reasonable price.

For income seekers Glaxo is the better choice, as the company currently supports a 4.9% dividend yield. Shire on the other hand, only offers a token 0.4% dividend yield. 

Moreover, as part of Glaxo’s asset-swap deal with Novartis, the company is planning to return around £4bn to investors. Just to put that into some perspective, Shire’s net profit for 2013 was only £400m around 10% of the amount Glaxo is planning to return to shareholders.

Foolish summary

All in all, choosing between Glaxo and Shire is difficult. However, after taking into account the fact that Glaxo is expected to return to growth next year and company currently offers an attractive 4.9% dividend yield, I have to say that Glaxo appears to be the better choice for income and growth. 

Rupert does not own any share mentioned within this article. The Motley Fool has recommended shares in Shire and GlaxoSmithKline. 

More on Investing Articles

Friends and sisters exploring the outdoors together in Cornwall. They are standing with their arms around each other at the coast.
Investing Articles

£503 buys 14 shares in this FTSE 250 stock that returned 23.9% annually for the last 15 years

This FTSE 250 stock has averaged a huge return for 15 years. At today's price, £503 buys 14 shares. But…

Read more »

Black woman using loudspeaker to be heard
Investing Articles

£1,000 buys 25 shares in this FTSE 100 stock that’s returned 29.2% annually for the last 10 years

This FTSE 100 mining stock has returned close to 30% a year for a decade. At 3,995p, £1,000 buys 25…

Read more »

Female student sitting at the steps and using laptop
Investing Articles

Down 47%, is this growth stock finally worth buying in May?

With a £288m order book and a hidden pipeline of defence and nuclear contracts, is this growth stock now too…

Read more »

House models and one with REIT - standing for real estate investment trust - written on it.
Investing Articles

2 REITs yielding 7%+ to consider for passive income in 2026

A REIT backed by the NHS and another backed by Tesco and Sainsbury's with both yielding 7%+. Here's why I'm…

Read more »

Woman riding her old fashioned bicycle along the Beach Esplanade at Aberdeen, Scotland.
Investing Articles

Just 97 shares of this UK dividend stock generate £238 in passive income

A 5.7% yield, £238 in passive income from just 97 shares, and one of the most divisive dividend stocks on…

Read more »

ISA coins
Investing Articles

£10,000 in an ISA generates a second income of…

The London Stock Exchange is home to some of the world's most generous dividends. But how big a second income…

Read more »

Shot of a senior man drinking coffee and looking thoughtfully out of a window
Investing Articles

Expert recommendations: 2 top income stocks yielding 7%+!

With yields of 7.2% and 7.8% respectively, these two income stocks are catching the eyes of institutional analysts. Should investors…

Read more »

Illustration of flames over a black background
Investing Articles

3 top income-focused stocks to buy in May 2026, according to experts

Looking for a stock to buy for income in May 2026? Experts have flagged these three UK dividend shares as…

Read more »