We have some exciting news to share! The Motley Fool UK has now become The Twelfth Magpie -- an independent, UK-owned company, led by our long-serving UK management team — Mark Rogers, Chris Nials and Heather Adlington. In practical terms, it’s the same team you know, now fully focused on serving our UK readers and members.

Just as importantly, our approach remains unchanged: long-term, jargon-free, and on your side. This site is our new home, and there will be extra tweaks made across the coming few days as we settle in. So if anything looks a little off, please bear with us!

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

Here’s Why AstraZeneca plc And Shire PLC Are Stronger Alone

AstraZeneca plc (LON: AZN) and Shire PLC (LON: SHP) are stronger as independent companies.

| More on:

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

If you were given the choice between receiving £1,000 now, or £2,000 in a years’ time, which would you take?

The answer should be simple, £2,000 in a years’ time would mean a risk-free return of 100% over a 12-month period — a return you’d be hard pressed to find elsewhere. 

XXX

Shareholders of AstraZeneca (LSE: AZN) and Shire (LSE: SHP) have recently been presented with a similar dilemma. Both companies have been subject to bids by larger peers over the past 12 months but over the long term, as standalone companies, the two groups will be able to achieve higher returns for investors.

Rapid growth  

Shire has traditionally been dependent upon treatments for attention deficit hyperactivity disorder but the company is now becoming increasingly focused on rare disease treatment. A small but lucrative market.

Just like Astra, Shire is planning to double annual sales to $10bn by 2020 and if the company achieves this growth, Shire’s shares could surge above the price of £53.19 per share offered for the company. 

Indeed, over the past five years Shires net profit margin has averaged 20%, although City analysts expect the group’s net margin to hit 35% over the next three years. If Shire’s revenue has increased to $10bn by 2020, a net margin of around 35% means that the group will report a net profit of $3.5bn, around £2.3bn. On a per share basis, £3.90 based on the current number of shares in issue.

Over the past 10 years Shire has traded at an average P/E of 20, which indicates that if earnings per share hit £3.90 by 2020, the company’s shares could be worth around £78.00, a 77% gain from present levels. Of course, these figures could change if the company decides buy back stock some of its own shares, a strategy many pharmaceutical companies employ to boost growth.  

Income investment 

It is possible to use the same kind of analysis to arrive at a long-term price target for Astra. The company is targeting sales of $45bn by 2023, based on historic margin figures, on revenue of $45bn the company could report a net profit of $9bn, around £5.6bn. This translates into earnings per share of £4.43.

Based on the fact that many high-growth pharmaceutical companies are currently trading at a P/E of 20, Astra’s shares could hit £88.60 over the next ten years — 88% above current levels. That’s excluding any dividend payments made along the way. Dividends could boost returns by around 4% per year.

And it’s likely that Astra’s payout will grow over time, in line with earnings, which makes the company a perfect candidate for any dividend portfolio.

Rupert Hargreaves has no position in any shares mentioned. The Motley Fool UK has no position in any of the shares mentioned. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Friends and sisters exploring the outdoors together in Cornwall. They are standing with their arms around each other at the coast.
Investing Articles

£503 buys 14 shares in this FTSE 250 stock that returned 23.9% annually for the last 15 years

This FTSE 250 stock has averaged a huge return for 15 years. At today's price, £503 buys 14 shares. But…

Read more »

Black woman using loudspeaker to be heard
Investing Articles

£1,000 buys 25 shares in this FTSE 100 stock that’s returned 29.2% annually for the last 10 years

This FTSE 100 mining stock has returned close to 30% a year for a decade. At 3,995p, £1,000 buys 25…

Read more »

Female student sitting at the steps and using laptop
Investing Articles

Down 47%, is this growth stock finally worth buying in May?

With a £288m order book and a hidden pipeline of defence and nuclear contracts, is this growth stock now too…

Read more »

House models and one with REIT - standing for real estate investment trust - written on it.
Investing Articles

2 REITs yielding 7%+ to consider for passive income in 2026

A REIT backed by the NHS and another backed by Tesco and Sainsbury's with both yielding 7%+. Here's why I'm…

Read more »

Woman riding her old fashioned bicycle along the Beach Esplanade at Aberdeen, Scotland.
Investing Articles

Just 97 shares of this UK dividend stock generate £238 in passive income

A 5.7% yield, £238 in passive income from just 97 shares, and one of the most divisive dividend stocks on…

Read more »

ISA coins
Investing Articles

£10,000 in an ISA generates a second income of…

The London Stock Exchange is home to some of the world's most generous dividends. But how big a second income…

Read more »

Shot of a senior man drinking coffee and looking thoughtfully out of a window
Investing Articles

Expert recommendations: 2 top income stocks yielding 7%+!

With yields of 7.2% and 7.8% respectively, these two income stocks are catching the eyes of institutional analysts. Should investors…

Read more »

Illustration of flames over a black background
Investing Articles

3 top income-focused stocks to buy in May 2026, according to experts

Looking for a stock to buy for income in May 2026? Experts have flagged these three UK dividend shares as…

Read more »