We have some exciting news to share! The Motley Fool UK has now become The Twelfth Magpie -- an independent, UK-owned company, led by our long-serving UK management team — Mark Rogers, Chris Nials and Heather Adlington. In practical terms, it’s the same team you know, now fully focused on serving our UK readers and members.

Just as importantly, our approach remains unchanged: long-term, jargon-free, and on your side. This site is our new home, and there will be extra tweaks made across the coming few days as we settle in. So if anything looks a little off, please bear with us!

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

Is Netscientific PLC A Better Buy Than Smith & Nephew plc And Dechra Pharmaceuticals plc?

Should you buy a slice of Netscientific PLC (LON: NSCI) before Smith & Nephew plc (LON: SN) and Dechra Pharmaceuticals plc (LON: DPH)?

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

Shares in Netscientific (LSE: NSCI) have enjoyed an extremely positive week, ending it around a third higher than they started it. The reason is positive news flow released yesterday, with Netscientific announcing that PDS Biotechnology, which is a company in its portfolio, has experienced positive preliminary data for its main cancer immunotherapy treatment, PDS0101. The drug has received a strong response in tests for its use on pre-cervical cancer, with it being shown to prime and activate T-cells, which play a crucial role in the human immune system.

In fact, PDS0101 could provide a clear alternative to the removal of lesions to overcome pre-cervical cancer (which is the current practice) and, as such, the market has reacted very favourably to the news flow. And, while shares in Netscientific are down by 12% today, it is likely to be a result of profit-taking after such a superb gain in Thursday’s trading session.

XXX

Diversity

Of course, Netscientific’s share price performance in the months prior to the announcement was very disappointing. Its shares fell from around 166p in January to as low as 110p in April. This shows that in the health care sector it is imperative to have diversity since, especially among companies that are heavily involved in research and development, volatility can be particularly high.

As such, investors seeking a less volatile shareholder experience may be better served by investing in a medical devices company such as Smith & Nephew (LSE: SN). It may not offer the same potential rewards as a smaller, research stock such as Netscientific, but it also comes with far less risk. For example, while Netscientific remains a loss-making company that is largely reliant upon the outcome of development programmes, Smith & Nephew has been hugely profitable in each of the last five years, with its bottom line set to grow by a further 13% next year, which is around twice the growth rate of the wider market.

Size And Scale

Furthermore, Netscientific remains a relatively small company with a market capitalisation of just £60m. Compare this to Dechra Pharmaceuticals (LSE: DPH), which has a market capitalisation of £928m and it is clear that the latter has significantly greater size and scale. While it could be argued that this makes Dechra less nimble than Netscientific, it could also mean that it has more stable finances and that it is a safer long term bet. And, with Dechra having increased its net profit at an average rate of 14% per annum during the last five years, it remains a relatively appealing growth play, too.

Looking Ahead

While Netscientific has performed extremely well in recent days, it remains a relatively high risk play. Certainly, it appears to have a bright future and news flow this week has been very positive, however it seems prudent to pair it up with larger, more robust peers that offer a degree of stability in the medium to long term. As such, a combination of Netscientific, Smith & Nephew and Dechra seems to be a sound move for longer-term investors.

Peter Stephens does not own shares in any of the companies mentioned.

More on Investing Articles

Friends and sisters exploring the outdoors together in Cornwall. They are standing with their arms around each other at the coast.
Investing Articles

£503 buys 14 shares in this FTSE 250 stock that returned 23.9% annually for the last 15 years

This FTSE 250 stock has averaged a huge return for 15 years. At today's price, £503 buys 14 shares. But…

Read more »

Black woman using loudspeaker to be heard
Investing Articles

£1,000 buys 25 shares in this FTSE 100 stock that’s returned 29.2% annually for the last 10 years

This FTSE 100 mining stock has returned close to 30% a year for a decade. At 3,995p, £1,000 buys 25…

Read more »

Female student sitting at the steps and using laptop
Investing Articles

Down 47%, is this growth stock finally worth buying in May?

With a £288m order book and a hidden pipeline of defence and nuclear contracts, is this growth stock now too…

Read more »

House models and one with REIT - standing for real estate investment trust - written on it.
Investing Articles

2 REITs yielding 7%+ to consider for passive income in 2026

A REIT backed by the NHS and another backed by Tesco and Sainsbury's with both yielding 7%+. Here's why I'm…

Read more »

Woman riding her old fashioned bicycle along the Beach Esplanade at Aberdeen, Scotland.
Investing Articles

Just 97 shares of this UK dividend stock generate £238 in passive income

A 5.7% yield, £238 in passive income from just 97 shares, and one of the most divisive dividend stocks on…

Read more »

ISA coins
Investing Articles

£10,000 in an ISA generates a second income of…

The London Stock Exchange is home to some of the world's most generous dividends. But how big a second income…

Read more »

Shot of a senior man drinking coffee and looking thoughtfully out of a window
Investing Articles

Expert recommendations: 2 top income stocks yielding 7%+!

With yields of 7.2% and 7.8% respectively, these two income stocks are catching the eyes of institutional analysts. Should investors…

Read more »

Illustration of flames over a black background
Investing Articles

3 top income-focused stocks to buy in May 2026, according to experts

Looking for a stock to buy for income in May 2026? Experts have flagged these three UK dividend shares as…

Read more »