We have some exciting news to share! The Motley Fool UK has now become The Twelfth Magpie -- an independent, UK-owned company, led by our long-serving UK management team — Mark Rogers, Chris Nials and Heather Adlington. In practical terms, it’s the same team you know, now fully focused on serving our UK readers and members.

Just as importantly, our approach remains unchanged: long-term, jargon-free, and on your side. This site is our new home, and there will be extra tweaks made across the coming few days as we settle in. So if anything looks a little off, please bear with us!

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

The Oxford Nanopore share price surged again! Should I buy now?

The Oxford Nanopore share price popped by double-digits following a trading update. Zaven Boyrazian investigates what it’s been up to.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

After an explosive IPO, the Oxford Nanopore (LSE:ONT) share price continues to surge. Last Friday, the stock popped as much as 16% in the first 15 minutes of trading. While selling pressure did bring the valuation back down in the afternoon, its performance since its public listing is still around +40%. So what caused this latest spike? And should I be considering this company for my portfolio? Let’s take a look.

Oxford Nanopore’s stellar share price performance

I’ve previously explored this business. But as a quick reminder, it’s a pioneering biotech institution that designs and manufactures DNA and RNA sequencing machines. This technology is paramount in the world of drug development, especially when it comes to understanding how a virus or disease works. Unsurprisingly, it’s been actively used throughout the last 18 months in the fight against Covid-19.

XXX

Last week, management provided a short and sweet trading update on the progress being made. While the pandemic may be slowly coming to an end, the demand for sequencing technology remains strong. And it’s not just Covid-19 driving sales. The business is also continuing to see demand coming from human genomic programmes. So much so that September saw a record-breaking sales performance.

That’s obviously excellent news for the business. And it would seem management agrees. Why? Because it just raised revenue growth guidance from 30-40% to 60-70% for the whole of 2021. So, seeing the Oxford Nanopore share price climb even higher on this news is hardly surprising to me.

Taking a step back

As exciting as this high growth is, my concerns surrounding this business’s valuation remain. In 2020, Oxford Nanopore reported total revenue of £113.9m. Assuming it can achieve the higher end of its forecast, that would place sales for 2021 at around £193.6m.

A near £80m jump in revenue is nothing to scoff at. But when taking the Oxford Nanopore share price into account, investors may be getting ahead of themselves. Today, the firm stands at a market capitalisation of around £4.8bn. That places the price-to-sales ratio at just under 25 times.

Needless to say, there’s a substantial premium being placed on this business by investors. If expectations aren’t met moving forward, the Oxford Nanopore share price could be the subject of a significant amount of volatility, especially since it has yet to turn profitable.

The bottom line

This latest update continues to show promise within the enterprise. And if Oxford Nanopore can continue growing at its current rate in a post-pandemic environment, I wouldn’t be surprised to see its share price climb even higher.

But with no precise data available, it’s hard to determine exactly what part of the business is the dominant force in driving sales. If this force is as a result of Covid-19, then the company may struggle to maintain its growth over the long term. Therefore, I’m still keeping this firm on my watchlist for now.

Zaven Boyrazian has no position in any of the shares mentioned. The Motley Fool UK has no position in any of the shares mentioned. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Friends and sisters exploring the outdoors together in Cornwall. They are standing with their arms around each other at the coast.
Investing Articles

£503 buys 14 shares in this FTSE 250 stock that returned 23.9% annually for the last 15 years

This FTSE 250 stock has averaged a huge return for 15 years. At today's price, £503 buys 14 shares. But…

Read more »

Black woman using loudspeaker to be heard
Investing Articles

£1,000 buys 25 shares in this FTSE 100 stock that’s returned 29.2% annually for the last 10 years

This FTSE 100 mining stock has returned close to 30% a year for a decade. At 3,995p, £1,000 buys 25…

Read more »

Female student sitting at the steps and using laptop
Investing Articles

Down 47%, is this growth stock finally worth buying in May?

With a £288m order book and a hidden pipeline of defence and nuclear contracts, is this growth stock now too…

Read more »

House models and one with REIT - standing for real estate investment trust - written on it.
Investing Articles

2 REITs yielding 7%+ to consider for passive income in 2026

A REIT backed by the NHS and another backed by Tesco and Sainsbury's with both yielding 7%+. Here's why I'm…

Read more »

Woman riding her old fashioned bicycle along the Beach Esplanade at Aberdeen, Scotland.
Investing Articles

Just 97 shares of this UK dividend stock generate £238 in passive income

A 5.7% yield, £238 in passive income from just 97 shares, and one of the most divisive dividend stocks on…

Read more »

ISA coins
Investing Articles

£10,000 in an ISA generates a second income of…

The London Stock Exchange is home to some of the world's most generous dividends. But how big a second income…

Read more »

Shot of a senior man drinking coffee and looking thoughtfully out of a window
Investing Articles

Expert recommendations: 2 top income stocks yielding 7%+!

With yields of 7.2% and 7.8% respectively, these two income stocks are catching the eyes of institutional analysts. Should investors…

Read more »

Illustration of flames over a black background
Investing Articles

3 top income-focused stocks to buy in May 2026, according to experts

Looking for a stock to buy for income in May 2026? Experts have flagged these three UK dividend shares as…

Read more »