We have some exciting news to share! The Motley Fool UK has now become The Twelfth Magpie -- an independent, UK-owned company, led by our long-serving UK management team — Mark Rogers, Chris Nials and Heather Adlington. In practical terms, it’s the same team you know, now fully focused on serving our UK readers and members.

Just as importantly, our approach remains unchanged: long-term, jargon-free, and on your side. This site is our new home, and there will be extra tweaks made across the coming few days as we settle in. So if anything looks a little off, please bear with us!

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

If I’d invested £500 in AstraZeneca shares 2 years ago, here’s how much I’d have now!

Dr James Fox explores whether AstraZeneca shares are right for his portfolio after two years of strong share-price growth.

| More on:
Young female business analyst looking at a graph chart while working from home

Image source: Getty Images

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

AstraZeneca (LSE:AZN) shares have been on my radar for some time. The stock is arguably the crown jewel of the FTSE 100 as the leading British biotech/pharma firm. And its share price growth will please investors — few companies have shown such consistent growth over the past 10 years.

Two-year growth

In 2020, AstraZeneca was a permanent news feature as various organisations raced to produce the first Covid-19 vaccine. Over the following year, the company was touted as a national saviour in the UK while European leaders wildly criticised the Astra vaccine — as a journalist at the time, I was writing about the company and its spats daily.

XXX

Over the past two years, the AstraZeneca share price has grown 35%. As such, if had bought £500 of AstraZeneca shares two years ago, today I’d have £675. That’s certainly a decent return, averaging 17.5% per annum.

 

In fact, the AstraZeneca growth story is impressive, regardless of the benchmark. Over three years, it’s up 40%, over five years it’s up 104%, and over 10 years, it’s closer to 300%.

What’s next for AstraZeneca?

In 2021, AstraZeneca had 12 drugs with revenues ranging between $1bn and $5bn annually. As an investor, this give us a sense of where each drug is in its product cycle. But it’s worth noting that the Vaxzevria Covid-19 vaccine was the company’s second largest revenue generator, at $3.9 billion.

The sales of the Covid-19 vaccine have really helped push revenue upwards. From the trailing 12 months, revenue is $44bn, up from $37bn in 2021, $26bn in 2020, and $24bn in 2019. City analysts are expecting a near-200% increase in earnings this year, with a further 13% in 2023.

However, this doesn’t give us too much visibility on the medium-to-long term. AstraZeneca has a mammoth pipeline with 184 projects in development right now. By comparison, Pfizer only has 104. It’s worth noting that many of these pipeline projects are label extensions rather than entirely new products. Regardless, it’s still impressive.

Equally impressive is the company’s commitment to expansion through acquisition. The Alexion Pharmaceuticals buy, for a whopping $38bn, gives AstraZeneca a commanding position in immunology medicine and rare diseases.

There’s also the recent deal for LogicBio Therapeutics, which is a pioneering genomic medicines company that focuses on genome editing and gene delivery for rare diseases. 

Should I buy the stock?

Amid global economic challenges, pharma has some defensive qualities that interest me. AstraZeneca will continue to sell its drugs around the world, regardless of whether economies go into recession.

The company is also likely to benefit from the weakness of the pound. Revenue in H1 was geographically varied. Around 38% came from the US, 28% from emerging markets, 20% from Europe, and 14% from the rest of the world. Foreign revenues will be inflated when converted back into GBP.

But more broadly, while there is always risk associated with biotechs and drug development, AstraZeneca’s expanding portfolio and increasing revenues puts in it a strong position. Because of the reasons noted, I’m looking to add the crown jewel of the FTSE 100 to my portfolio.

James Fox has no position in any of the shares mentioned. The Motley Fool UK has no position in any of the shares mentioned. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Friends and sisters exploring the outdoors together in Cornwall. They are standing with their arms around each other at the coast.
Investing Articles

£503 buys 14 shares in this FTSE 250 stock that returned 23.9% annually for the last 15 years

This FTSE 250 stock has averaged a huge return for 15 years. At today's price, £503 buys 14 shares. But…

Read more »

Black woman using loudspeaker to be heard
Investing Articles

£1,000 buys 25 shares in this FTSE 100 stock that’s returned 29.2% annually for the last 10 years

This FTSE 100 mining stock has returned close to 30% a year for a decade. At 3,995p, £1,000 buys 25…

Read more »

Female student sitting at the steps and using laptop
Investing Articles

Down 47%, is this growth stock finally worth buying in May?

With a £288m order book and a hidden pipeline of defence and nuclear contracts, is this growth stock now too…

Read more »

House models and one with REIT - standing for real estate investment trust - written on it.
Investing Articles

2 REITs yielding 7%+ to consider for passive income in 2026

A REIT backed by the NHS and another backed by Tesco and Sainsbury's with both yielding 7%+. Here's why I'm…

Read more »

Woman riding her old fashioned bicycle along the Beach Esplanade at Aberdeen, Scotland.
Investing Articles

Just 97 shares of this UK dividend stock generate £238 in passive income

A 5.7% yield, £238 in passive income from just 97 shares, and one of the most divisive dividend stocks on…

Read more »

ISA coins
Investing Articles

£10,000 in an ISA generates a second income of…

The London Stock Exchange is home to some of the world's most generous dividends. But how big a second income…

Read more »

Shot of a senior man drinking coffee and looking thoughtfully out of a window
Investing Articles

Expert recommendations: 2 top income stocks yielding 7%+!

With yields of 7.2% and 7.8% respectively, these two income stocks are catching the eyes of institutional analysts. Should investors…

Read more »

Illustration of flames over a black background
Investing Articles

3 top income-focused stocks to buy in May 2026, according to experts

Looking for a stock to buy for income in May 2026? Experts have flagged these three UK dividend shares as…

Read more »