We have some exciting news to share! The Motley Fool UK has now become The Twelfth Magpie -- an independent, UK-owned company, led by our long-serving UK management team — Mark Rogers, Chris Nials and Heather Adlington. In practical terms, it’s the same team you know, now fully focused on serving our UK readers and members.

Just as importantly, our approach remains unchanged: long-term, jargon-free, and on your side. This site is our new home, and there will be extra tweaks made across the coming few days as we settle in. So if anything looks a little off, please bear with us!

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

Down 50% with a 6.5% yield, is this massive S&P 500 stock a screaming buy?

Our writer considers the prospects of a once-massive S&P 500 stock that’s fallen out of favour and now has a low price and attractive dividend yield.

| More on:
A black male doctor chats to a senior patient on the hospital ward ,with a young female nurse wearing a hijab attending to a dressing

Image source: Getty Images

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

During the pandemic, it was one of the most well-known S&P 500 companies in the world. Famous for being the first to develop an FDA-approved Covid vaccine, Pfizer (NYSE: PFE) quickly became a household name.

Today, the pharma giant’s market-cap has collapsed over 50% from its Covid-era high of $333.8bn. Now at around $150bn, it no longer holds a place in the largest 100 companies in the world.

XXX

As the pandemic ended, the huge influx of revenue from vaccine sales tapered off. In the ensuing years, the share price fell to a 10-year low. But Pfizer is not just a vaccine company. It also develops treatments for a range of medical conditions such as cancer, sickle cell disease and arthritis.

So is the falling share price indicative of wider issues or simply an expected correction after Covid?

Business as usual

Pfizer doesn’t appear to be struggling in the face of falling revenues. In 2022, it acquired the immuno-inflammatory company Arena Pharmaceuticals and the following year, Seagen, an oncology specialist.

But vaccines remain one of its biggest focus areas. Its success during Covid means it’s in good stead to be the company of choice for vaccine development. It currently has a strong pipeline for the development of new mRNA-based flu and RSV vaccines.

Valuation

The falling price means the stock is now trading at 67% below fair value based on future cash flow estimates. Plus, earnings are forecast to grow at a rate of 15.7% a year. 

That gives the stock an attractive forward price-to-earnings (P/E) ratio of 13. As such, analysts expect price growth of 25% on average in the coming 12 months.

Challenges

Like many pharmaceutical companies, Pfizer faces the imminent and terrifying patent cliff. As the expiration dates of its major drug patents draw near, it faces the risk of competition from generics and biosimilars.

Not only does it face competition from generic developers but also major pharmaceutical players like Merck, Johnson & Johnson and Novartis. It can’t rely on another pandemic to boost sales — if it hopes to remain relevant, it needs to outperform its competitors.

In the past, it suffered reputational damage from the high pricing of EpiPens and cancer drugs. With a recent uptick in debates around healthcare pricing in the US, a forced reevaluation of its pricing model could limit revenues.

My verdict

Pfizer remains a strong business that seems to be performing well and expanding effectively. The 6.5% yield makes the current low price particularly attractive. Grabbing some cheap shares now could set an investor up for lucrative returns over the coming years.

Without a doubt, there are challenges, particularly those related to the wider healthcare controversy in the US. However, the company’s worst losses appear to be over with the stock trading up during Q3 this year. If the economy enjoys a boost in 2025 under the new Trump administration, it stands to benefit. 

With Christmas coming, I don’t have spare cash to put into new stocks right now. However, for investors looking to diversify into US pharmaceuticals, I think Pfizer is worth considering.

Mark Hartley has no position in any of the shares mentioned. The Motley Fool UK has no position in any of the shares mentioned. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Friends and sisters exploring the outdoors together in Cornwall. They are standing with their arms around each other at the coast.
Investing Articles

£503 buys 14 shares in this FTSE 250 stock that returned 23.9% annually for the last 15 years

This FTSE 250 stock has averaged a huge return for 15 years. At today's price, £503 buys 14 shares. But…

Read more »

Black woman using loudspeaker to be heard
Investing Articles

£1,000 buys 25 shares in this FTSE 100 stock that’s returned 29.2% annually for the last 10 years

This FTSE 100 mining stock has returned close to 30% a year for a decade. At 3,995p, £1,000 buys 25…

Read more »

Female student sitting at the steps and using laptop
Investing Articles

Down 47%, is this growth stock finally worth buying in May?

With a £288m order book and a hidden pipeline of defence and nuclear contracts, is this growth stock now too…

Read more »

House models and one with REIT - standing for real estate investment trust - written on it.
Investing Articles

2 REITs yielding 7%+ to consider for passive income in 2026

A REIT backed by the NHS and another backed by Tesco and Sainsbury's with both yielding 7%+. Here's why I'm…

Read more »

Woman riding her old fashioned bicycle along the Beach Esplanade at Aberdeen, Scotland.
Investing Articles

Just 97 shares of this UK dividend stock generate £238 in passive income

A 5.7% yield, £238 in passive income from just 97 shares, and one of the most divisive dividend stocks on…

Read more »

ISA coins
Investing Articles

£10,000 in an ISA generates a second income of…

The London Stock Exchange is home to some of the world's most generous dividends. But how big a second income…

Read more »

Shot of a senior man drinking coffee and looking thoughtfully out of a window
Investing Articles

Expert recommendations: 2 top income stocks yielding 7%+!

With yields of 7.2% and 7.8% respectively, these two income stocks are catching the eyes of institutional analysts. Should investors…

Read more »

Illustration of flames over a black background
Investing Articles

3 top income-focused stocks to buy in May 2026, according to experts

Looking for a stock to buy for income in May 2026? Experts have flagged these three UK dividend shares as…

Read more »