We have some exciting news to share! The Motley Fool UK has now become The Twelfth Magpie -- an independent, UK-owned company, led by our long-serving UK management team — Mark Rogers, Chris Nials and Heather Adlington. In practical terms, it’s the same team you know, now fully focused on serving our UK readers and members.

Just as importantly, our approach remains unchanged: long-term, jargon-free, and on your side. This site is our new home, and there will be extra tweaks made across the coming few days as we settle in. So if anything looks a little off, please bear with us!

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

Why AstraZeneca plc shares could be the buy of the decade

AstraZeneca plc’s (LON:AZN) share price could double in five years, says G A Chester.

| More on:

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

Investors in AstraZeneca (LSE: AZN) in the early years of the 21st century endured a long period of frustration. The shares peaked at just over 3,500p in 2002 and it took until 2013 for them to break through that level again.

The renewed optimism followed a boardroom shake-up in 2012 when investor unrest over the underperforming share price, falling sales and a dearth of new medicines saw the departure of both the chairman and chief executive.

XXX

Sales have remained under pressure due to expiring patents on some of the company’s major products, but the market has warmed increasingly to Astra’s future prospects. The shares are now trading at around 5,000p but I believe they’re set to rise much higher.

Turnaround

When new chief executive Pascal Soriot arrived he found a company that was “imploding” and in need of radical overhaul. Research — the lifeblood of a pharma company — was sprawling, inefficient and lacking in dynamism and new ideas.

Soriot has shrunk its operations to focus on core areas like cancer, respiratory and cardiovascular disease. He’s moved the business closer, both culturally and physically, to cutting-edge academic research. It’s taken time but Astra now has one of the strongest pipelines in the industry.

Trough year

The business hasn’t quite reached the inflection point of a return to growth but it’s fast approaching. It reported in its Q3 results that the impact from the loss of exclusivity on its products is starting to recede and laid out the major news flow on the pipeline it expects through 2018 — an impressive list of regulatory submissions and decisions.

City analysts expect 2018 to be the trough year for earnings. The consensus forecast gives a P/E of 18.3 but this comes down to 16.3 for 2019 on expectations of earnings growth kicking in for the first time. One of Soriot’s achievements for shareholders has been to maintain the company’s dividend throughout the overhaul of the business. As such, buyers of the shares today have a prospective yield of around 4%. However, I believe this could be just the topping on far more substantial capital gains.

Buy of the decade?

Even when earnings were falling and Soriot’s turnaround strategy was in its infancy, Astra was viewed as a valuable franchise by trade players. In 2014, he persuaded shareholders to reject a 5,500p a share offer from US giant Pfizer. He argued that the terms “substantially undervalue AstraZeneca” and pledged to achieve revenues of $45bn by 2023.

He may have made himself a hostage to fortune — the target is ambitious — but if he can deliver anywhere near that kind of revenue, the rewards for investors are likely to be substantial. Astra generated revenue of $23bn in its last financial year, making a net profit of $3.5bn at a margin of a bit over 15%. Roll on to revenue of $45bn at the same margin in 2023 and we’d be looking at a net profit of $6.8bn. Furthermore, an improvement in the margin to nearer 20% (net profit $9bn) wouldn’t be entirely fanciful.

I see the stock as a good buy today, taking a considerably more conservative view of growth prospects, but if the company does achieve its ambitious targets, it could be the buy of the decade, certainly among its big pharma peers.

G A Chester has no position in any of the shares mentioned. The Motley Fool UK has recommended AstraZeneca. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Friends and sisters exploring the outdoors together in Cornwall. They are standing with their arms around each other at the coast.
Investing Articles

£503 buys 14 shares in this FTSE 250 stock that returned 23.9% annually for the last 15 years

This FTSE 250 stock has averaged a huge return for 15 years. At today's price, £503 buys 14 shares. But…

Read more »

Black woman using loudspeaker to be heard
Investing Articles

£1,000 buys 25 shares in this FTSE 100 stock that’s returned 29.2% annually for the last 10 years

This FTSE 100 mining stock has returned close to 30% a year for a decade. At 3,995p, £1,000 buys 25…

Read more »

Female student sitting at the steps and using laptop
Investing Articles

Down 47%, is this growth stock finally worth buying in May?

With a £288m order book and a hidden pipeline of defence and nuclear contracts, is this growth stock now too…

Read more »

House models and one with REIT - standing for real estate investment trust - written on it.
Investing Articles

2 REITs yielding 7%+ to consider for passive income in 2026

A REIT backed by the NHS and another backed by Tesco and Sainsbury's with both yielding 7%+. Here's why I'm…

Read more »

Woman riding her old fashioned bicycle along the Beach Esplanade at Aberdeen, Scotland.
Investing Articles

Just 97 shares of this UK dividend stock generate £238 in passive income

A 5.7% yield, £238 in passive income from just 97 shares, and one of the most divisive dividend stocks on…

Read more »

ISA coins
Investing Articles

£10,000 in an ISA generates a second income of…

The London Stock Exchange is home to some of the world's most generous dividends. But how big a second income…

Read more »

Shot of a senior man drinking coffee and looking thoughtfully out of a window
Investing Articles

Expert recommendations: 2 top income stocks yielding 7%+!

With yields of 7.2% and 7.8% respectively, these two income stocks are catching the eyes of institutional analysts. Should investors…

Read more »

Illustration of flames over a black background
Investing Articles

3 top income-focused stocks to buy in May 2026, according to experts

Looking for a stock to buy for income in May 2026? Experts have flagged these three UK dividend shares as…

Read more »